Free amino acids of the Yoshida ascites tumor.

amounts of free taurine, alanine, glycine, and glutamic acid and smaller amounts of a number of other ninhydrin-reactive constituents being found (8@, 88, 85). A characteristic feature of the tumor patterns has been the finding that the level of glutamine has been generally below the level of detection of the chromatographic procedures. However, free glutamine appears when tumors be gin to regress (83). All normal tissues examined have shown the presence of glutamine. The present report is concerned with studies of the free amino acids of the fluid and cells of the Yoshida ascites sarcoma, an easily manipulated neoplasm which has been particularly well studied from a cytological point of view (@8, @9, 81, 48).